Hancock Jaffe Laboratories, Inc. is a medical device company in its developmental stage, specializing in creating advanced tissue-based and biologic solutions. These innovations are engineered to either sustain or significantly enhance the lives of patients afflicted with cardiovascular, peripheral arterial, and venous diseases, as well as end-stage renal disease (ESRD). The firm, headquartered in Irvine, California, maintains a dedicated team of nine full-time employees. Among its key initiatives, the company is actively developing implantable bioprosthetic devices for cardiovascular applications. This includes the Bioprosthetic Heart Valve (BHV), a swine-derived heart valve designed to mimic the function of a native heart valve and provide superior performance compared to current prosthetic options. Furthermore, the company is developing a Venous Valve, another bioprosthetic device sourced from pig tissue. This valve is specifically designed for individuals suffering from chronic venous insufficiency (CVI) in the lower limbs, a condition frequently resulting from damage to leg vein valves after the formation of deep venous blood clots.